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We have 3 hotels in Edwardsville.

 
 
Country Hearth Inn Edwardsville Star Rating 3        
1013 Plummer Dr

A block from biking and hiking on the Madison County Trails, this casual hotel is set in a 3-story brick building just off Highway 157.The relaxed rooms feature free WiFi, minifridges, microwaves and flat-screen TVs. Some suites add recliners, sofabeds, kitchenettes and/or whirlpool tubs.
Comfort Inn Edwardsville Star Rating 2        
3080 S. Sr 157

This 4-story hotel and conference center is less than a mile from Interstate 270 and 1.8 miles from the Southern Illinois University, while the attractions of St. Louis are a 20-mile drive away.
Holiday Inn Express and Suites Edwardsville Star Rating 3        
1000 Plummer Drive

In a modern building off Highway 157, this relaxed hotel is 2 miles from the Edwardsville Children's Museum and 9 miles from the Lewis and Clark State Historic Site.The bright contemporary rooms feature pillow-top mattresses and flat-screen TVs, along with minifridges, microwaves and free Wi-Fi. Suites add wet bars, dining tables, and living areas with pull-out sofas.
 
 
More on Edwardsville .
 
Edwardsville is a city in Madison County, Illinois, United States. As of the 2010 census, the city population was 24,293. It is the county seat of Madison County and is the third oldest city in the State of Illinois.